I am afraid this will happen to me soon. I already don't really have "friends," but I still at least make regular social contact with "acquaintances." When I graduate, I will only be more isolated. I don't want to live a life where the only social stimulation I get is from my coworkers or whatever.
I suppose I never really developed the "skills" to go out and make friends. I was always passive in that regard; if people happened to like being around me, they would become my friends.